Transactions of Nonferrous Metals Society of China The Chinese Journal of Nonferrous Metals

您目前所在的位置:首页 - 期刊简介 - 详细页面


Transactions of Nonferrous Metals Society of China

Vol. 29    No. 12    December 2019

[PDF Download]        


Effects of pore size and porosity of surface-modified porous titanium implants on bone tissue ingrowth
Jing-pu ZHENG1, Liang-jian CHEN1,2, Dai-yuan CHEN1, Chun-sheng SHAO1, Man-fei YI1, Bo ZHANG1

1. Department of Stomatology, Third Xiangya Hospital, Central South University, Changsha 410013, China;
2. State Key Laboratory of Powder Metallurgy, Central South University, Changsha 410083, China

Abstract:The effects of surface-modified porous titanium implants with different porosities and pore sizes on osseointegration were investigated in vivo. Three porous titanium implants (A30, A40 and A50 containing volume fractions of space-holder NaCl being 30%, 40% and 50%, respectively) were manufactured by metal injection moulding (MIM). The surface-modified implants were implanted into muscles and femurs of hybrid male dogs. Interface osteogenic activity and histological bone ingrowth of porous titanium implants were evaluated at 28, 56 and 84 d. The results showed that when additive space-holder amount of NaCl increased from 30% to 50% (volume fraction), the general porosity and mass fraction of macropores of porous titanium rose from 42.4% to 62.0% and from 8.3% to 69.3%, respectively. Histologic sections and fluorescent labeling showed that the A50 implant demonstrated a significantly higher osteogenic capacity at 28 d than other implants. Bone ingrowth into the A30 implant was lower than that into other implants at 84 d. Therefore, the pore structure of A50 implant was suitable for new bone tissue to grow into porous implant.


Key words: porous titanium implant; porosity; aperture; interconnectivity; osseointegration

ISSN 1004-0609
CN 43-1238/TG

ISSN 1003-6326
CN 43-1239/TG

主管:中国科学技术协会 主办:中国有色金属学会 承办:中南大学
湘ICP备09001153号 版权所有:《中国有色金属学报》编辑部
地 址:湖南省长沙市岳麓山中南大学内 邮编:410083
电 话:0731-88876765,88877197,88830410   传真:0731-88877197   电子邮箱